Live from the WWE ThunderDome inside Tropicana Field in St. Petersburg, Florida, WWE presents Fastlane 2021 on pay-per-view and WWE Network. The full card is as follows:

Roman Reigns vs Daniel Bryan for the Universal title with Edge as the special enforcer; Big E vs Apollo Crews for the Intercontinental title; Nia Jax and Shayna Baszler vs Sasha Banks and Bianca Belair for the WWE Women’s Tag Team titles; Riddle vs Mustafa Ali; Drew McIntyre vs Sheamus in a no holds barred match; Shinsuke Nakamura vs Seth Rollins; and Alexa Bliss vs Randy Orton in an intergender match.

Fastlane is the first WWE pay-per-view to air on Peacock and the last one that will air on the U.S. version of the WWE Network.